Monica Dayam

Monica Dayam
Postdoctoral Fellow
Warren Alpert Building, Room 138
Roaya.Dayam [at]
Current Projects

I am trying to identify factors that mediate Antisense oligonucleotides (ASOs) uptake and the underlying mechanisms on how ASOs are released from the internalized compartments (i.e. endocytic compartments). To do that, I established a high-throughput CRISPR (clustered regularly interspaced short palindromic repeats) screen during which genes are disrupted on a whole-genomic scale in a reporter cell line, which expresses the reporter system and Cas9. The screen will help us  identify genes that are essential for ASO uptake and activity.

Alumni Graduation Year
Alumni Present Position

Research associate, Cellular/Molecular Biologist. Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto Canada