Publications

Hoffman, D. P. Shtengel, G. Xu, C. S. Campbell, K. R. Freeman, M. Wang, L. Milkie, D. E. Pasolli, H. A. Iyer, N. Bogovic, J. A. Stabley, D. R. Shirinifard, A. Pang, S. Peale, D. Schaefer, K. Pomp, W. Chang, C. L. Lippincott-Schwartz, J. Kirchhausen, T. Solecki, D. J. Betzig, E. Hess, H. F.

Within cells, the spatial compartmentalization of thousands of distinct proteins serves a multitude of diverse biochemical needs. Correlative super-resolution (SR) fluorescence and electron microscopy (EM) can elucidate protein spatial relationships to global ultrastructure, but has suffered from tradeoffs of structure preservation, fluorescence retention, resolution, and field of view. We developed a platform for three-dimensional cryogenic SR and focused ion beam-milled block-face EM across entire vitreously frozen cells. The approach preserves ultrastructure while enabling independent SR and EM workflow optimization. We discovered unexpected protein-ultrastructure relationships in mammalian cells including intranuclear vesicles containing endoplasmic reticulum-associated proteins, web-like adhesions between cultured neurons, and chromatin domains subclassified on the basis of transcriptional activity. Our findings illustrate the value of a comprehensive multimodal view of ultrastructural variability across whole cells.

PDF
He, K. Song, E. Upadhyayula, S. Dang, S. Gaudin, R. Skillern, W. Bu, K. Capraro, B. R. Rapoport, I. Kusters, I. Ma, M. Kirchhausen, T.

Clathrin-coated vesicles lose their clathrin lattice within seconds of pinching off, through the action of the Hsc70 "uncoating ATPase." The J- and PTEN-like domain-containing proteins, auxilin 1 (Aux1) and auxilin 2 (GAK), recruit Hsc70. The PTEN-like domain has no phosphatase activity, but it can recognize phosphatidylinositol phosphate head groups. Aux1 and GAK appear on coated vesicles in successive transient bursts, immediately after dynamin-mediated membrane scission has released the vesicle from the plasma membrane. These bursts contain a very small number of auxilins, and even four to six molecules are sufficient to mediate uncoating. In contrast, we could not detect auxilins in abortive pits or at any time during coated pit assembly. We previously showed that clathrin-coated vesicles have a dynamic phosphoinositide landscape, and we have proposed that lipid head group recognition might determine the timing of Aux1 and GAK appearance. The differential recruitment of Aux1 and GAK correlates with temporal variations in phosphoinositide composition, consistent with a lipid-switch timing mechanism.

PDF
Pascolutti, R. Algisi, V. Conte, A. Raimondi, A. Pasham, M. Upadhyayula, S. Gaudin, R. Maritzen, T. Barbieri, E. Caldieri, G. Tordonato, C. Confalonieri, S. Freddi, S. Malabarba, M. G. Maspero, E. Polo, S. Tacchetti, C. Haucke, V. Kirchhausen, T. Di Fiore, P. P. Sigismund, S.

Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in mammalian cells is an open issue. Here, we demonstrate, by live TIRF microscopy, the existence of a subclass of relatively short-lived CCPs lacking AP2 under physiological, unperturbed conditions. This subclass is retained in AP2-knockout cells and is able to support the internalization of epidermal growth factor receptor (EGFR) but not of transferrin receptor (TfR). The AP2-independent internalization mechanism relies on the endocytic adaptors eps15, eps15L1, and epsin1. The absence of AP2 impairs the recycling of the EGFR to the cell surface, thereby augmenting its degradation. Accordingly, under conditions of AP2 ablation, we detected dampening of EGFR-dependent AKT signaling and cell migration, arguing that distinct classes of CCPs could provide specialized functions in regulating EGFR recycling and signaling.

PDF
Calzoni, E. Platt, C. D. Keles, S. Kuehn, H. S. Beaussant-Cohen, S. Zhang, Y. Pazmandi, J. Lanzi, G. Pala, F. Tahiat, A. Artac, H. Heredia, R. J. Dmytrus, J. Reisli, I. Uygun, V. Uygun, D. Bingol, A. Basaran, E. Djenouhat, K. Benhalla, N. Bendahmane, C. Emiroglu, M. Kirchhausen, T. Pasham, M. Jones, J. Wallace, J. G. Zheng, L. Boisson, B. Porta, F. Rosenzweig, S. D. Su, H. Giliani, S. Lenardo, M. Geha, R. S. Boztug, K. Chou, J. Notarangelo, L. D.
PDF
Gao, R., Asano, S. M., Upadhyayula, S., Pisarev, I., Milkie, D. E., Liu, T.-L., Singh, V., Graves, A., Huynh, G. H., Zhao, Y., Bogovic, J., Colonell, J., Ott, C. M., Zugates, C., Tappan, S., Rodriguez, A., Mosaliganti, K. R., Megason, S. G., Lippincott-Schwartz, J., Hantman, A., Rubin, G. M., Kirchhausen, T., Saalfeld, S., Aso, Y., Boyden, E. S. & Betzig, E.
PDF
Bocking, T. Upadhyayula, S. Rapoport, I. Capraro, B. R. Kirchhausen, T.
PDF
Coulter, M. E. Dorobantu, C. M. Lodewijk, G. A. Delalande, F. Cianferani, S. Ganesh, V. S. Smith, R. S. Lim, E. T. Xu, C. S. Pang, S. Wong, E. T. Lidov, H. G. W. Calicchio, M. L. Yang, E. Gonzalez, D. M. Schlaeger, T. M. Mochida, G. H. Hess, H. Lee, W. A. Lehtinen, M. K. Kirchhausen, T. Haussler, D. Jacobs, F. M. J. Gaudin, R. Walsh, C. A.
PDF
Swinburne, I. A. Mosaliganti, K. R. Upadhyayula, S. Liu, T. L. Hildebrand, D. G. C. Tsai, T. Y. Chen, A. Al-Obeidi, E. Fass, A. K. Malhotra, S. Engert, F. Lichtman, J. W. Kirchausen, T. Betzig, E. Megason, S. G.

Elife

PDF
Liu, T. L. Upadhyayula, S. Milkie, D. E. Singh, V. Wang, K. Swinburne, I. A. Mosaliganti, K. R. Collins, Z. M. Hiscock, T. W. Shea, J. Kohrman, A. Q. Medwig, T. N. Dambournet, D. Forster, R. Cunniff, B. Ruan, Y. Yashiro, H. Scholpp, S. Meyerowitz, E. M. Hockemeyer, D. Drubin, D. G. Martin, B. L. Matus, D. Q. Koyama, M. Megason, S. G. Kirchhausen, T. Betzig, E.

Science

PDF
Liu, T. L. Upadhyayula, S. Milkie, D. E. Singh, V. Wang, K. Swinburne, I. A. Mosaliganti, K. R. Collins, Z. M. Hiscock, T. W. Shea, J. Kohrman, A. Q. Medwig, T. N. Dambournet, D. Forster, R. Cunniff, B. Ruan, Y. Yashiro, H. Scholpp, S. Meyerowitz, E. M. Hockemeyer, D. Drubin, D. G. Martin, B. L. Matus, D. Q. Koyama, M. Megason, S. G. Kirchhausen, T. Betzig, E.

bioRvix

PDF
Swinburne, I. A. Mosaliganti, K. R. Upadhyayula, S. Liu, T. L. Hildebrand, D. G. C. Tsai, T. Y. Chen, A. Al-Obeidi, E. Fass, A. K. Malhotra, S. Engert, F. Lichtman, J. W. Kirchausen, T. Betzig, E. Megason, S. G.

bioRvix

PDF
He, K. Marsland Iii, R. Upadhyayula, S. Song, E. Dang, S. Capraro, B. R. Wang, W. Skillern, W. Gaudin, R. Ma, M. Kirchhausen, T.

Nature

PDF
Bruna S. Paulsen, Pankaj K. Mandal, Richard L. Frock, Baris Boyraz, Rachita Yadav, Srigokul Upadhyayula, Paula Gutierrez-Martinez, Wataru Ebina, Anders Fasth, Tomas Kirchhausen, Michael E. Talkowski, Suneet Agarwal, Frederick W. Alt & Derrick J. Rossi

Nat. Biomed. Eng. 1, 878–888, 2017 Oct 09

PDF
Raaben, M. Jae, L. T. Herbert, A. S. Kuehne, A. I. Stubbs, S. H. Chou, Y. Y. Blomen, V. A. Kirchhausen, T. Dye, J. M. Brummelkamp, T. R. Whelan, S. P.

Cell Host Microbe, Volume 22, issue 5, pages 688-696 e5

PDF
Adell, M. A. Y. Migliano, S. M. Upadhyayula, S. Bykov, Y. S. Sprenger, S. Pakdel, M. Vogel, G. F. Jih, G. Skillern, W. Behrouzi, R. Babst, M. Schmidt, O. Hess, M. W. Briggs, J. A. Kirchhausen, T. Teis, D.

Elife, Volume 6, Oct 11

PDF
Schuler, M. H. Lewandowska, A. Di Caprio, G. Skillern, W. Upadhyayula, S. Kirchhausen, T. Shaw, J. M. Cunniff, B.

Mol Biol Cell (2017)

PDF
Chou, Y. Y Cuevas, C Carocci, M Stubbs, S. H Ma, M Cureton, D. K Chao, L Evesson, F He, K Yang, P. L Whelan, S. P Ross, S. R Kirchhausen, T Gaudin, R.

Journal of virology (2016)

PDF
Aguet, F Upadhyayula, S Gaudin, R Chou, Y. Y Cocucci, E He, K Chen, B. C Mosaliganti, K Pasham, M Skillern, W Legant, W. R Liu, T. L Findlay, G Marino, E Danuser, G Megason, S Betzig, E Kirchhausen, T.

Molecular biology of the cell (2016)

PDF
Meyer, P. A Socias, S Key, J Ransey, E Tjon, E. C Buschiazzo, A Lei, M Botka, C Withrow, J Neau, D Rajashankar, K Anderson, K. S Baxter, R. H Blacklow, S. C Boggon, T. J Bonvin, A. M Borek, D Brett, T. J Caflisch, A Chang, C. I Chazin, W. J Corbett, K. D Cosgrove, M. S Crosson, S Dhe-Paganon, S Di Cera, E Drennan, C. L Eck, M. J Eichman, B. F Fan, Q. R Ferre-D'Amare, A. R Christopher Fromme, J Garcia, K. C Gaudet, R Gong, P Harrison, S. C Heldwein, E. E Jia, Z Keenan, R. J Kruse, A. C Kvansakul, M McLellan, J. S Modis, Y Nam, Y Otwinowski, Z Pai, E. F Pereira, P. J Petosa, C Raman, C. S Rapoport, T. A Roll-Mecak, A Rosen, M. K Rudenko, G Schlessinger, J Schwartz, T. U Shamoo, Y Sondermann, H Tao, Y. J Tolia, N. H Tsodikov, O. V Westover, K. D Wu, H Foster, I Fraser, J. S Maia, F. R Gonen, T Kirchhausen, T Diederichs, K Crosas, M Sliz, P.

Nature communications (2016), Volume: 7, Pages: 10882

PDF
Wang, H Becuwe, M Housden, B. E Chitraju, C Porras, A. J Graham, M. M Liu, X. N Thiam, A. R Savage, D. B Agarwal, A. K Garg, A Olarte, M. J Lin, Q Frohlich, F Hannibal-Bach, H. K Upadhyayula, S Perrimon, N Kirchhausen, T Ejsing, C. S Walther, T. C Farese, R. V.

eLife (2016), Volume: 5

PDF
Hu Y, Kim JH, He K, Wan Q, Kim J, Flach M, Kirchhausen T,

The Journal of experimental medicine (2016)

PDF
Yi-Ying Chou, Annabel Krupp, Campbell Kaynor, Raphaël Gaudin, Minghe Ma, Ellen Cahir-McFarland, Tom Kirchhausen

Sci Rep (2016)

PDF
Antonny, B Burd, C De Camilli, P Chen, E Daumke, O Faelber, K Ford, M Frolov, V. A Frost, A Hinshaw, J. E Kirchhausen, T Kozlov, M. M Lenz, M Low, H. H McMahon, H Merrifield, C Pollard, T. D Robinson, P. J Roux, A Schmid, S.

The EMBO journal (2016)

PDF
Li, D Shao, L Chen, B. C Zhang, X Zhang, M Moses, B Milkie, D. E Beach, J. R Hammer, J. A., 3rdPasham, M Kirchhausen, T Baird, M. A Davidson, M. W Xu, P Betzig, E.

Science (2015), Volume: 349, Issue: 6251, Pages: aab3500

PDF
Bourzac, K.

Nature (2015), Volume: 526, Issue: 7574, Pages: S50-4

PDF
Gaudin, R Kirchhausen, T.

Scientific reports (2015), Volume: 5, Pages: 15990

PDF
Kural, C Akatay, A. A Gaudin, R Chen, B. C Legant, W. R Betzig, E Kirchhausen, T.

Molecular biology of the cell (2015)

PDF
Wittrup, A Ai, A Liu, X Hamar, P Trifonova, R Charisse, K Manoharan, M Kirchhausen, T Lieberman, J.

Nature biotechnology (2015), Volume: 33, Issue: 8, Pages: 870-6

PDF
Abdelhakim, A. H Salgado, E. N Fu, X Pasham, M Nicastro, D Kirchhausen, T Harrison, S. C.

PLoS pathogens (2014), Volume: 10, Issue: 9, Pages: e1004355

PDF
Ishikawa, Y Maeda, M Pasham, M Aguet, F Tacheva-Grigorova, S. K Masuda, T Yi, H Lee, S Xu, J Teruya-Feldstein, J Ericsson, M Mullally, A Heuser, J Kirchhausen, T Maeda, T.

Haematologica (2014)

PDF
Cocucci, E Gaudin, R Kirchhausen, T.

Molecular biology of the cell (2014)

PDF
Hagemann, A. I Kurz, J Kauffeld, S Chen, Q Reeves, P. M Weber, S Schindler, S Davidson, G Kirchhausen, T Scholpp, S.

Journal of cell science (2014)

PDF
Walch, M Dotiwala, F Mulik, S Thiery, J Kirchhausen, T Clayberger, C Krensky, A. M Martinvalet, D Lieberman, J.

Cell (2014), Volume: 157, Issue: 6, Pages: 1309-1323

PDF
Bocking, T Aguet, F Rapoport, I Banzhaf, M Yu, A Zeeh, J. C Kirchhausen, T.

Structure (2014)

PDF
Carmo-Fonseca, M Kirchhausen, T.

Nucleus (2014), Volume: 5, Issue: 1

PDF
Kirchhausen, T Owen, D Harrison, S. C.

Cold Spring Harbor perspectives in biology (2014), Volume: 6, Issue: 5

PDF
Martin, R. M Rino, J Carvalho, C Kirchhausen, T Carmo-Fonseca, M.

Cell Reports (2013)

PDF
Boulant, S Stanifer, M Kural, C Cureton, D. K Massol, R Nibert, M. L Kirchhausen, T.

Molecular biology of the cell (2013)

PDF
Tacheva-Grigorova, S. K Santos, A. J Boucrot, E Kirchhausen, T.

Cell Reports (2013), Volume: 4, Issue: 4, Pages: 659-68

PDF
Piccinotti, S Kirchhausen, T Whelan, S. P.

Journal of Virology (2013)

PDF
Martinelli, R Kamei, M Sage, P. T Massol, R Varghese, L Sciuto, T Toporsian, M Dvorak, A. M Kirchhausen, T Springer, T. A Carman, C. V.

The Journal of cell biology (2013), Volume: 201, Issue: 3, Pages: 449-65

PDF
Heesters, B. A Chatterjee, P Kim, Y. A Gonzalez, S. F Kuligowski, M. P Kirchhausen, T Carroll, M. C.

Immunity (2013), Volume: 38, Issue: 6, Pages: 1164-75

PDF
Lu, L Hannoush, R. N Goess, B. C Varadarajan, S Shair, M. D Kirchhausen, T.

Molecular biology of the cell (2013)

PDF
Kural, C Kirchhausen, T.

Methods Enzymol (2012), Volume: 505, Pages: 59-80

PDF
Tom Kirchhausen

Nat Cell Biol (2012), Volume: 14, Issue: 9, Pages: 906-8

PDF
Willems, E Cabral-Teixeira, J Schade, D Cai, W Reeves, P Bushway, P. J Lanier, M Walsh, C Kirchhausen, T Izpisua Belmonte, J. C Cashman, J Mercola, M.

Cell Stem Cell (2012), Volume: 11, Issue: 2, Pages: 242-52

PDF
Cocucci, E Aguet, F Boulant, S Kirchhausen, T.

Cell (2012), Volume: 150, Issue: 3, Pages: 495-507

PDF
Kural, C Tacheva-Grigorova, S. K Boulant, S Cocucci, E Baust, T Duarte, D Kirchhausen, T.

Cell Rep (2012)

PDF
Lu, L Kirchhausen, T.

Commun Integr Biol (2012), Volume: 5, Issue: 1, Pages: 16-18

PDF
Hori, K Sen, A Kirchhausen, T Artavanis-Tsakonas, S.

Commun Integr Biol (2012), Volume: 5, Issue: 4, Pages: 374-6

PDF
Strang, B. L Boulant, S Kirchhausen, T Coen, D. M.

MBio (2012), Volume: 3, Issue: 1

PDF
Cureton, D. K Harbison, C. E Cocucci, E Parrish, C. R Kirchhausen, T.

J Virol (2012)

PDF
Lu, L Ladinsky, M. S Kirchhausen, T.

J Cell Biol (2011), Volume: 194, Issue: 3, Pages: 425-40

PDF
Ivanovic, T Boulant, S Ehrlich, M Demidenko, A. A Arnold, M. M Kirchhausen, T Nibert, M. L.

Traffic (2011)

PDF
Bocking, T Aguet, F Harrison, S. C Kirchhausen, T.

Nat Struct Mol Biol (2011), Volume: 18, Issue: 3, Pages: 295-301

PDF
Boulant, S Kural, C Zeeh, J. C Ubelmann, F Kirchhausen, T.

Nat Cell Biol (2011), Volume: 13, Issue: 9, Pages: 1124-31

PDF
Thiery, J Keefe, D Boulant, S Boucrot, E Walch, M Martinvalet, D Goping, I. S Bleackley, R. C Kirchhausen, T Lieberman, J.

Nat Immunol (2011)

PDF
Bai, M Gad, H Turacchio, G Cocucci, E Yang, J. S Li, J Beznoussenko, G. V Nie, Z Luo, R Fu, L Collawn, J. F Kirchhausen, T Luini, A Hsu, V. W.

Nat Cell Biol (2011), Volume: 13, Issue: 5, Pages: 559-67

PDF
Boucrot, E Howes, M. T Kirchhausen, T Parton, R. G.

J Cell Sci (2011), Volume: 124, Issue: Pt 12, Pages: 1965-72

PDF
Strang, B. L Boulant, S Chang, L Knipe, D. M Kirchhausen, T Coen, D. M.

J Virol (2011)

PDF
Hori, K Sen, A Kirchhausen, T Artavanis-Tsakonas, S.

J Cell Biol (2011), Volume: 195, Issue: 6, Pages: 1005-15

PDF
Anitei, M., Stange, C., Parshina, I., Baust, T., Schenck, A., Raposo, G., Kirchhausen, T., Hoflack, B.

Nat Cell Biol (2010), Volume: 12, Issue: 4, Pages: 330-40

PDF
Yi Xing, Till Böcking, Matthias Wolf, Nikolaus Grigorieff, Tomas Kirchhausen and Stephen C. Harrison

Embo (2010), Volume: 29, Issue: 3, Pages: 655-65

PDF
Smits, P., et al.

N Engl J Med (2010), Volume: 362, Issue: 3, Pages: 206-16

PDF
Cureton, D. K., Massol, R. H., Whelan, S. P. and Kirchhausen, T.

PLoS Pathogens (2010), Volume: 6, Issue: 9

PDF
Yu, A., Xing, Y., Harrison, S. C. and Kirchhausen, T.

Structure (2010), Volume: 18, Issue: 10, Pages: 1311-20

PDF
Guan, R., Han, D., Harrison, S. C., Kirchhausen, T.

Structure (2010), Volume: 18, Issue: 9, Pages: 1191-8

PDF
Audrun Utskarpen, Ramiro Massol, Bo van Deurs, Silje Ugland Lauvrak, Tomas Kirchhausen, Kirsten Sandvig

PloS One (2010), Volume: 5, Issue: 7, Pages: e10944

PDF
Harrison, S.C., Kirchhausen, T.

Nature (2010), Volume: 466, Issue: 7310, Pages: 1048-9

PDF
Boucrot, E., Saffarian, S., Zhang, R., Kirchhausen, T.

PloS One (2010), Volume: 5, Issue: 5, Pages: e110597

PDF
Jerome Thiery, Dennis Keefe, Saviz Saffarian, Denis Martinvalet, Michael Walch, Emmanuel Boucrot, Tomas Kirchhausen and Judy Lieberman

Blood (2009)

PDF
Cureton DK, Massol RH, Saffarian S, Kirchhausen TL, Whelan SP

PLoS pathogens (2009), Volume: 5, Issue: 4, Pages: e1000394

PDF
Shulman Z, Shinder V, Klein E, Grabovsky V, Yeger O et al

Immunity (2009), Volume: 30, Issue: 3, Pages: 384-396

PDF
T. Kirchhausen

Trends Cell Biol (2009), Volume: 19, Issue: 11, Pages: 596-605

PDF
Lu L, Ladinsky MS, Kirchhausen T

Molecular biology of the cell (2009), Volume: 20, Issue: 15, Pages: 3471-80

PDF
Saveez Saffarian, Emanuele Cocucci, Tomas Kirchhausen

PloS Biol (2009), Volume: 7, Issue: 9, Pages: e1000191

PDF
Saffarian, S.; Kirchhausen, T.

Biophys J (2008), Volume: 94, Issue: 6, Pages: 2333-42

PDF
Nieland, T. J.; Shaw, J. T.; Jaipuri, F. A.; Duffner, J. L.; Koehler, A. N.; Banakos, S.; Zannis, V. I.; Kirchhausen, T.; Krieger, M.

Biochemistry (2008), Volume: 47, Issue: 1, Pages: 460-72

PDF
Boucrot, E.; Kirchhausen, T.

PloS ONE (2008), Volume: 3, Issue: 1, Pages: e1477

PDF
Ambrogio, C.; Voena, C.; Manazza, A. D.; Martinengo, C.; Costa, C.; Kirchhausen, T.; Hirsch, E.; Inghirami, G.; Chiarle, R.

Cancer Res (2008), Volume: 68, Issue: 21, Pages: 8899-907

PDF
Kirchhausen, T.; Macia, E.; Pelish, H. E.

Meth Enzymol (2008), Volume: 438, Pages: 77-93

PDF
Rapoport, I.; Boll, W.; Yu, A.; Bocking, T.; Kirchhausen, T.

Mol Biol Cell (2008), Volume: 19, Issue: 1, Pages: 405-13

PDF
Yu, A.; Rual, J. F.; Tamai, K.; Harada, Y.; Vidal, M.; He, X.; Kirchhausen, T.

Dev Cell (2007), Volume: 12, Issue: 1, Pages: 129-41

PDF
Li, J.; Peters, P. J.; Bai, M.; Dai, J.; Bos, E.; Kirchhausen, T.; Kandror, K. V.; Hsu, V. W.

J Cell Biol (2007), Volume: 178, Issue: 3, Pages: 453-64

PDF
Kirchhausen, T.

Cell (2007), Volume: 129, Issue: 7, Pages: 1251-2

PDF
Ma, Y. M.; Boucrot, E.; Villen, J.; Affar el, B.; Gygi, S. P.; Gottlinger, H. G.; Kirchhausen, T.

J Biol Chem (2007), Volume: 282, Issue: 13, Pages: 9805-12

PDF
Wang, J.; Sun, H. Q.; Macia, E.; Kirchhausen, T.; Watson, H.; Bonifacino, J. S.; Yin, H. L.

Mol Biol Cell (2007), Volume: 18, Issue: 7, Pages: 2646-55

PDF
Cheng, Y.; Boll, W.; Kirchhausen, T.; Harrison, S. C.; Walz, T.

J Mol Biol (2007), Volume: 365, Issue: 3, Pages: 892-9

PDF
Veiga, E.; Guttman, J. A.; Bonazzi, M.; Boucrot, E.; Toledo-Arana, A.; Lin, A. E.; Enninga, J.; Pizarro-Cerda, J.; Finlay, B. B.; Kirchhausen, T.; Cossart, P.

Cell Host Microbe (2007), Volume: 2, Issue: 5, Pages: 340-51

PDF
Jiang, S.; Zhou, X.; Kirchhausen, T.; Wong, S. T.

(2007), Volume: 71, Issue: 8, Pages: 576-84

PDF
Jiang, S.; Zhou, X.; Kirchhausen, T.; Wong, S. T.

Cytometry (2007), Volume: 71, Issue: 8, Pages: 563-75

PDF
Boucrot, E.; Kirchhausen, T.

Proc Natl Acad Sci (2007), Volume: 104, Issue: 19, Pages: 7939-44

PDF
Fotin, A.; Kirchhausen, T.; Grigorieff, N.; Harrison, S. C.; Walz, T.; Cheng, Y.

J Struct Biol (2006), Volume: 156, Issue: 3, Pages: 453-60

PDF
Macia, E.; Ehrlich, M.; Massol, R.; Boucrot, E.; Brunner, C.; Kirchhausen, T.

Dev Cell (2006), Volume: 10, Issue: 6, Pages: 839-50

PDF
Massol, R. H.; Boll, W.; Griffin, A. M.; Kirchhausen, T.

Proc Natl Acad Sci (2006), Volume: 103, Issue: 27, Pages: 10265-70

PDF
Pelish, H. E.; Peterson, J. R.; Salvarezza, S. B.; Rodriguez-Boulan, E.; Chen, J. L.; Stamnes, M.; Macia, E.; Feng, Y.; Shair, M. D.; Kirchhausen, T.

Nat Chem Biol (2006), Volume: 2, Issue: 1, Pages: 39-46

PDF
Pelish, H. E.; Ciesla, W.; Tanaka, N.; Reddy, K.; Shair, M. D.; Kirchhausen, T.; Lencer, W. I.

Biochem Pharmacol (2006), Volume: 71, Issue: 12, Pages: 1720-6

PDF
Xu, B.; Pelish, H.; Kirchhausen, T.; Hammond, G. B.

Org Biomol (2006), Volume: 4, Issue: 22, Pages: 4149-57

PDF
Goess, B. C.; Hannoush, R. N.; Chan, L. K.; Kirchhausen, T.; Shair, M. D.

J Am Chem (2006), Volume: 128, Issue: 16, Pages: 5391-403

PDF
Boucrot, E.; Saffarian, S.; Massol, R.; Kirchhausen, T.; Ehrlich, M.

Exp Cell (2006), Volume: 312, Issue: 20, Pages: 4036-48

PDF
Newton, A. J.; Kirchhausen, T.; Murthy, V. N.

Proc Natl Acad Sci (2006), Volume: 103, Issue: 47, Pages: 17955-60

PDF
Falcone, S.; Cocucci, E.; Podini, P.; Kirchhausen, T.; Clementi, E.; Meldolesi, J.

J Cell Sci (2006), Volume: 119, Issue: Pt 22, Pages: 4758-69

PDF
Keefe, D.; Shi, L.; Feske, S.; Massol, R.; Navarro, F.; Kirchhausen, T.; Lieberman, J.

Immunity (2005), Volume: 23, Issue: 3, Pages: 249-62

PDF
McNeil, P. L.; Kirchhausen, T.

Nat Rev Mol Cell Biol (2005), Volume: 6, Issue: 6, Pages: 499-505

PDF
Nieland, T. J.; Ehrlich, M.; Krieger, M.; Kirchhausen, T.

Biochim Biophys Acta (2005), Volume: 1734, Issue: 1, Pages: 44-51

PDF
Massol, R. H.; Larsen, J. E.; Kirchhausen, T.

Exp Cell Res (2005), Volume: 306, Issue: 1, Pages: 142-9

PDF
Benedito, A. B.; Lehtinen, M.; Massol, R.; Lopes, U. G.; Kirchhausen, T.; Rao, A.; Bonni, A.

J Biol Chem (2005), Volume: 280, Issue: 4, Pages: 2818-25

PDF
Kirchhausen, T.; Boll, W.; van Oijen, A.; Ehrlich, M.

Biochem Soc Symp (2005), Issue: 72, Pages: 71-6

PDF
Paleotti, O.; Macia, E.; Luton, F.; Klein, S.; Partisani, M.; Chardin, P.; Kirchhausen, T.; Franco, M.

J Biol Chem (2005), Volume: 280, Issue: 22, Pages: 21661-6

PDF
Massol, R. H.; Larsen, J. E.; Fujinaga, Y.; Lencer, W. I.; Kirchhausen, T.

Mol Biol Cell (2004), Volume: 15, Issue: 8, Pages: 3631-41

PDF
Nieland, T. J.; Feng, Y.; Brown, J. X.; Chuang, T. D.; Buckett, P. D.; Wang, J.; Xie, X. S.; McGraw, T. E.; Kirchhausen, T.; Wessling-Resnick, M.

Traffic (2004), Volume: 5, Issue: 7, Pages: 478-92

PDF
Cerny, J.; Feng, Y.; Yu, A.; Miyake, K.; Borgonovo, B.; Klumperman, J.; Meldolesi, J.; McNeil, P. L.; Kirchhausen, T.

EMBO Rep (2004), Volume: 5, Issue: 9, Pages: 883-8

PDF
Larsen, J. E.; Massol, R. H.; Nieland, T. J.; Kirchhausen, T.

Mol Biol Cell (2004), Volume: 15, Issue: 1, Pages: 323-31

PDF
Boll, W.; Ehrlich, M.; Collier, R. J.; Kirchhausen, T.

Eur J Cell Biol (2004), Volume: 83, Issue: 6, Pages: 281-8

PDF
Fotin, A.; Cheng, Y.; Grigorieff, N.; Walz, T.; Harrison, S. C.; Kirchhausen, T.

Nature (2004), Volume: 432, Issue: 7017, Pages: 649-53

PDF
Heldwein, E. E.; Macia, E.; Wang, J.; Yin, H. L.; Kirchhausen, T.; Harrison, S. C.

Proc Natl Acad Sci (2004), Volume: 101, Issue: 39, Pages: 14108-13

PDF
Ehrlich, M.; Boll, W.; Van Oijen, A.; Hariharan, R.; Chandran, K.; Nibert, M. L.; Kirchhausen, T.

Cell (2004), Volume: 118, Issue: 5, Pages: 591-605

PDF
Fotin, A.; Cheng, Y.; Sliz, P.; Grigorieff, N.; Harrison, S. C.; Kirchhausen, T.; Walz, T.

Nature (2004), Volume: 432, Issue: 7017, Pages: 573-9

PDF
Feng, Y.; Jadhav, A. P.; Rodighiero, C.; Fujinaga, Y.; Kirchhausen, T.; Lencer, W. I.

EMBO Rep (2004), Volume: 5, Issue: 6, Pages: 596-601

PDF
Nieland, T. J.; Chroni, A.; Fitzgerald, M. L.; Maliga, Z.; Zannis, V. I.; Kirchhausen, T.; Krieger, M.

J Lipid Res (2004), Volume: 45, Issue: 7, Pages: 1256-65

PDF
Wang, Y. J.; Wang, J.; Sun, H. Q.; Martinez, M.; Sun, Y. X.; Macia, E.; Kirchhausen, T.; Albanesi, J. P.; Roth, M. G.; Yin, H. L.

Cell (2003), Volume: 114, Issue: 3, Pages: 299-310

PDF
Boes, M.; Bertho, N.; Cerny, J.; Op den Brouw, M.; Kirchhausen, T.; Ploegh, H.

J Immunol (2003), Volume: 171, Issue: 8, Pages: 4081-8

PDF
Yarrow, J. C.; Feng, Y.; Perlman, Z. E.; Kirchhausen, T.; Mitchison, T. J.

Come Chem High (2003), Volume: 6, Issue: 4, Pages: 279-86

PDF
Legesse-Miller, A.; Massol, R. H.; Kirchhausen, T.

Mol Biol Cell (2003), Volume: 14, Issue: 5, Pages: 1953-63

PDF
Chandran, K.; Parker, J. S.; Ehrlich, M.; Kirchhausen, T.; Nibert, M. L.

(2003), Volume: 77, Issue: 24, Pages: 13361-75

PDF
Feng, Y.; Yu, S.; Lasell, T. K.; Jadhav, A. P.; Macia, E.; Chardin, P.; Melancon, P.; Roth, M.; Mitchison, T.; Kirchhausen, T.

Proc Natl Acad Sci (2003), Volume: 100, Issue: 11, Pages: 6469-74

PDF
Schaefer, A. W.; Kamei, Y.; Kamiguchi, H.; Wong, E. V.; Rapoport, I.; Kirchhausen, T.; Beach, C. M.; Landreth, G.; Lemmon, S. K.; Lemmon, V.

J Cell Biol (2002), Volume: 157, Issue: 7, Pages: 1223-32

PDF
Nieland, T. J.; Penman, M.; Dori, L.; Krieger, M.; Kirchhausen, T.

Proc Natl Acad Sci (2002), Volume: 99, Issue: 24, Pages: 15422-7

PDF
Boll, W.; Rapoport, I.; Brunner, C.; Modis, Y.; Prehn, S.; Kirchhausen, T.

Traffic (2002), Volume: 3, Issue: 8, Pages: 590-600

PDF
Kirchhausen, T.

Cell (2002), Volume: 109, Issue: 4, Pages: 413-6

PDF
Kirchhausen, T.

Nat Struct Biol (2002), Volume: 9, Issue: 4, Pages: 241-4

PDF
Boes, M.; Cerny, J.; Massol, R.; Op den Brouw, M.; Kirchhausen, T.; Chen, J.; Ploegh, H. L.

Nature (2002), Volume: 418, Issue: 6901, Pages: 983-8

PDF
Pelish, H. E.; Westwood, N. J.; Feng, Y.; Kirchhausen, T.; Shair, M. D.

J Am Chem (2001), Volume: 123, Issue: 27, Pages: 6740-1

PDF
Lederkremer, G. Z.; Cheng, Y.; Petre, B. M.; Vogan, E.; Springer, S.; Schekman, R.; Walz, T.; Kirchhausen, T.

Proc Natl Acad Sci (2001), Volume: 98, Issue: 19, Pages: 10704-9

PDF
Kirchhausen, T.

Nat Rev Mol Cell Biol (2000), Volume: 1, Issue: 3, Pages: 187-98

PDF
Farr, G. W.; Furtak, K.; Rowland, M. B.; Ranson, N. A.; Saibil, H. R.; Kirchhausen, T.; Horwich, A. L.

Cell (2000), Volume: 100, Issue: 5, Pages: 561-73

PDF
Kirchhausen, T.

Annu Rev Biochem (2000), Volume: 69, Pages: 699-727

PDF
Chen, F.; Ma, L.; Parrini, M. C.; Mao, X.; Lopez, M.; Wu, C.; Marks, P. W.; Davidson, L.; Kwiatkowski, D. J.; Kirchhausen, T.; Orkin, S. H.; Rosen, F. S.; Mayer, B. J.; Kirschner, M. W.; Alt, F. W.

Curr Biol (2000), Volume: 10, Issue: 13, Pages: 758-65

PDF
ter Haar, E.; Harrison, S. C.; Kirchhausen, T.

Proc Natl Acad Sci (2000), Volume: 97, Issue: 3, Pages: 1096-100

PDF
Kirchhausen, T.

Nature (1999), Volume: 398, Issue: 6727, Pages: 470-1

PDF
Rohatgi, R.; Ma, L.; Miki, H.; Lopez, M.; Kirchhausen, T.; Takenawa, T.; Kirschner, M. W.

Cell (1999), Volume: 97, Issue: 2, Pages: 221-31

PDF
Musacchio, A.; Smith, C. J.; Roseman, A. M.; Harrison, S. C.; Kirchhausen, T.; Pearse, B. M.

Mol Cell (1999), Volume: 3, Issue: 6, Pages: 761-70

PDF
Schneider, H.; Martin, M.; Agarraberes, F. A.; Yin, L.; Rapoport, I.; Kirchhausen, T.; Rudd, C. E.

J Immunol (1999), Volume: 163, Issue: 4, Pages: 1868-79

PDF
Jones, A. T.; Spiro, D. J.; Kirchhausen, T.; Melancon, P.; Wessling-Resnick, M.

J Cell Sci (1999), Volume: 112 ( Pt 20), Pages: 3477-85

PDF
Kirchhausen, T.

Annu Rev Cell Dev Biol (1999), Volume: 15, Pages: 705-32

PDF
ter Haar, E.; Musacchio, A.; Harrison, S. C.; Kirchhausen, T.

Cell (1998), Volume: 95, Issue: 4, Pages: 563-73

PDF
Kamiguchi, H.; Long, K. E.; Pendergast, M.; Schaefer, A. W.; Rapoport, I.; Kirchhausen, T.; Lemmon, V.

J Neuroscience (1998), Volume: 18, Issue: 14, Pages: 5311-21

PDF
Kirchhausen, T.

Molecular medicine today (1998), Volume: 4, Issue: 7, Pages: 300-4

PDF
Rapoport, I.; Chen, Y. C.; Cupers, P.; Shoelson, S. E.; Kirchhausen, T.

EMBO J (1998), Volume: 17, Issue: 8, Pages: 2148-55

PDF
Kirchhausen, T.

Curr Biol (1998), Volume: 8, Issue: 22, Pages: R792-4

PDF
Tong, X.; Boll, W.; Kirchhausen, T.; Howley, P. M.

J Virol (1998), Volume: 72, Issue: 1, Pages: 476-82

PDF
Greenberg, M.; DeTulleo, L.; Rapoport, I.; Skowronski, J.; Kirchhausen, T.

Curr Biol (1998), Volume: 8, Issue: 22, Pages: 1239-42

PDF
Sanderfoot, A. A.; Ahmed, S. U.; Marty-Mazars, D.; Rapoport, I.; Kirchhausen, T.; Marty, F.; Raikhel, N. V.

Proc Natl Acad Sci (1998), Volume: 95, Issue: 17, Pages: 9920-5

PDF
Cupers, P.; Jadhav, A. P.; Kirchhausen, T.

J Biol Chem (1998), Volume: 273, Issue: 4, Pages: 1847-50

PDF
DeTulleo, L.; Kirchhausen, T.

EMBO J (1998), Volume: 17, Issue: 16, Pages: 4585-93

PDF
Kirchhausen, T.; Pines, J.; Toldo, L.; Lafont, F.

Curr Opin Cell Biol (1997), Volume: 9, Issue: 4, Pages: 473

PDF
Clairmont, K. B.; Boll, W.; Ericsson, M.; Kirchhausen, T.

Cell Mol Life Sci (1997), Volume: 53, Issue: 7, Pages: 611-9

PDF
Kirchhausen, T.; Bonifacino, J. S.; Riezman, H.

Curr Opin Cell Biol (1997), Volume: 9, Issue: 4, Pages: 488-95

PDF
Cupers, P.; ter Haar, E.; Boll, W.; Kirchhausen, T.

J Biol Chem (1997), Volume: 272, Issue: 52, Pages: 33430-4

PDF
Rapoport, I.; Miyazaki, M.; Boll, W.; Duckworth, B.; Cantley, L. C.; Shoelson, S.; Kirchhausen, T.

EMBO J (1997), Volume: 16, Issue: 9, Pages: 2240-50

PDF
Kolluri, R.; Tolias, K. F.; Carpenter, C. L.; Rosen, F. S.; Kirchhausen, T.

Proc Natl Acad Sci (1996), Volume: 93, Issue: 11, Pages: 5615-8

PDF
Bonifacino, J. S.; Marks, M. S.; Ohno, H.; Kirchhausen, T.

(1996), Volume: 108, Issue: 4, Pages: 285-95

Kirchhausen, T.; Rosen, F. S.

(1996), Volume: 6, Issue: 6, Pages: 676-8

PDF
Tebar, F.; Sorkina, T.; Sorkin, A.; Ericsson, M.; Kirchhausen, T.

J Biol Chem (1996), Volume: 271, Issue: 46, Pages: 28727-30

PDF
Bunnell, S. C.; Henry, P. A.; Kolluri, R.; Kirchhausen, T.; Rickles, R. J.; Berg, L. J.

J Biol Chem (1996), Volume: 271, Issue: 41, Pages: 25646-56

PDF
Boll, W.; Ohno, H.; Songyang, Z.; Rapoport, I.; Cantley, L. C.; Bonifacino, J. S.; Kirchhausen, T.

EMBO J (1996), Volume: 15, Issue: 21, Pages: 5789-95

PDF
Spiro, D. J.; Boll, W.; Kirchhausen, T.; Wessling-Resnick, M.

Mol Biol Cell (1996), Volume: 7, Issue: 3, Pages: 355-67

PDF
Stepp, J. D.; Pellicena-Palle, A.; Hamilton, S.; Kirchhausen, T.; Lemmon, S. K.

Mol Biol Cell (1995), Volume: 6, Issue: 1, Pages: 41-58

PDF
Ohno, H.; Stewart, J.; Fournier, M. C.; Bosshart, H.; Rhee, I.; Miyatake, S.; Saito, T.; Gallusser, A.; Kirchhausen, T.; Bonifacino, J. S.

Science (1995), Volume: 269, Issue: 5232, Pages: 1872-5

PDF
Speelman, B. A.; Allen, K.; Grounds, T. L.; Neutra, M. R.; Kirchhausen, T.; Wilson, J. M.

J Biol Chem (1995), Volume: 270, Issue: 4, Pages: 1583-8

PDF
Sorkin, A.; McKinsey, T.; Shih, W.; Kirchhausen, T.; Carpenter, G.

J Biol Chem (1995), Volume: 270, Issue: 2, Pages: 619-25

PDF
Boll, W.; Gallusser, A.; Kirchhausen, T.

Curr Biol (1995), Volume: 5, Issue: 10, Pages: 1168-78

PDF
Shih, W.; Gallusser, A.; Kirchhausen, T.

J Biol Chem (1995), Volume: 270, Issue: 52, Pages: 31083-90

PDF
Rad, M. R.; Phan, H. L.; Kirchrath, L.; Tan, P. K.; Kirchhausen, T.; Hollenberg, C. P.; Payne, G. S.

J Cell Sci (1995), Volume: 108 ( Pt 4), Pages: 1605-15

PDF
Phan, H. L.; Finlay, J. A.; Chu, D. S.; Tan, P. K.; Kirchhausen, T.; Payne, G. S.

EMBO J (1994), Volume: 13, Issue: 7, Pages: 1706-17

PDF
Osborn, L.; Vassallo, C.; Browning, B. G.; Tizard, R.; Haskard, D. O.; Benjamin, C. D.; Dougas, I.; Kirchhausen, T.

J Cell Biol (1994), Volume: 124, Issue: 4, Pages: 601-8

PDF
Sogaard, M.; Tani, K.; Ye, R. R.; Geromanos, S.; Tempst, P.; Kirchhausen, T.; Rothman, J. E.; Sollner, T.

Cell (1994), Volume: 78, Issue: 6, Pages: 937-48

PDF
Gallusser, A.; Kirchhausen, T.

EMBO J (1993), Volume: 12, Issue: 13, Pages: 5237-44

PDF
Kirchhausen, T.; Staunton, D. E.; Springer, T. A.

J Leukoc Biol (1993), Volume: 53, Issue: 3, Pages: 342-6

PDF
Kirchhausen, T.; Toyoda, T.

J Biol Chem (1993), Volume: 268, Issue: 14, Pages: 10268-73

PDF
Nakayama, Y.; Goebl, M.; O'Brine Greco, B.; Lemmon, S.; Pingchang Chow, E.; Kirchhausen, T.

Eur J Biochem (1991), Volume: 202, Issue: 2, Pages: 569-74

PDF
Kirchhausen, T.; Davis, A. C.; Frucht, S.; Greco, B. O.; Payne, G. S.; Tubb, B.

J Biol Chem (1991), Volume: 266, Issue: 17, Pages: 11153-7

PDF
Keen, J. H.; Beck, K. A.; Kirchhausen, T.; Jarrett, T.

J Biol Chem (1991), Volume: 266, Issue: 12, Pages: 7950-6

PDF
Scarmato, P.; Kirchhausen, T.

J Biol Chem (1990), Volume: 265, Issue: 7, Pages: 3661-8

PDF
Tucker, K. L.; Nathanson, K.; Kirchhausen, T.

Nucleic Acids Res (1990), Volume: 18, Issue: 17, Pages: 5306

PDF
Matsui, W.; Kirchhausen, T.

Biochemistry (1990), Volume: 29, Issue: 48, Pages: 10791-8

PDF
Kirchhausen, T.; Nathanson, K. L.; Matsui, W.; Vaisberg, A.; Chow, E. P.; Burne, C.; Keen, J. H.; Davis, A. E.

Proc Natl Acad Sci (1989), Volume: 86, Issue: 8, Pages: 2612-6

PDF
Thurieau, C.; Brosius, J.; Burne, C.; Jolles, P.; Keen, J. H.; Mattaliano, R. J.; Chow, E. P.; Ramachandran, K. L.; Kirchhausen, T.

DNA (1988), Volume: 7, Issue: 10, Pages: 663-9

PDF
Kirchhausen, T.; Scarmato, P.; Harrison, S. C.; Monroe, J. J.; Chow, E. P.; Mattaliano, R. J.; Ramachandran, K. L.; Smart, J. E.; Ahn, A. H.; Brosius, J.

Science (1987), Volume: 236, Issue: 4799, Pages: 320-4

PDF
Kirchhausen, T.; Harrison, S. C.; Chow, E. P.; Mattaliano, R. J.; Ramachandran, K. L.; Smart, J.; Brosius, J.

Proc Natl Acad Sci (1987), Volume: 84, Issue: 24, Pages: 8805-9

PDF
Kirchhausen, T.; Harrison, S. C.; Heuser, J.

J Ultrastruct Mol (1986), Volume: 94, Issue: 3, Pages: 199-208

PDF
Kirchhausen, T.; Wang, J. C.; Harrison, S. C.

Cell (1985), Volume: 41, Issue: 3, Pages: 933-43

PDF
Heuser, J.; Kirchhausen, T.

Journal of Ultrastructure Research (1985), Volume: 92, Issue: 1-2, Pages: 1-27

PDF
Kirchhausen, T.; Harrison, S. C.

J Cell Biol (1984), Volume: 99, Issue: 5, Pages: 1725-34

PDF
Harrison, S. C.; Kirchhausen, T.

Cell (1983), Volume: 33, Issue: 3, Pages: 650-2

PDF
Kirchhausen, T.; Harrison, S. C.; Parham, P.; Brodsky, F. M.

Proc Natl Acad Sci (1983), Volume: 80, Issue: 9, Pages: 2481-5

PDF
Hogle, J.; Kirchhausen, T.; Harrison, S. C.

J Mol Biol (1983), Volume: 171, Issue: 1, Pages: 95-100

PDF
Leon, V.; Kirchhausen, T.; Avila, E. M.; Mateu, L.

Acta Cient (1983), Volume: 34, Issue: 3-4, Pages: 209-15

PDF
Fless, G. M.; Kirchhausen, T.; Fischer-Dzoga, K.; Wissler, R. W.; Scanu, A. M.

Atherosclerosis (1982), Volume: 41, Issue: 2-3, Pages: 171-83

PDF
Kirchhausen, T.; Harrison, S. C.

Cell (1981), Volume: 23, Issue: 3, Pages: 755-61

PDF
Kirchhausen, T.; Fless, G.; Scanu, A. M.

Lipids (1980), Volume: 15, Issue: 6, Pages: 464-7

PDF
Kirchhausen, T.; Untracht, S. H.; Fless, G. M.; Scanu, A. M.

(1979), Volume: 33, Issue: 1, Pages: 59-70

Mateu, L.; Kirchhausen, T.; Camejo, G.

Biochemistry (1978), Volume: 17, Issue: 8, Pages: 1436-40

PDF
Mateu, L.; Kirchhausen, T.; Padron, R.; Camejo, G.

J Supramol Struct (1977), Volume: 7, Issue: 3-4, Pages: 435-42

PDF
Mateu, L.; Kirchhausen, T.; Camejo, G.

Biochim Biophys Acta (1977), Volume: 487, Issue: 1, Pages: 243-5

PDF